Methyltestosterone is 17-alpha-methyl altered so that the hormone can survive its first pass through the liver, and be effective as an oral agent, rather than just being destroyed by the liver. Unfortunately, this alteration also puts stress on the liver and contributes to the hepatoxicity (liver toxicity) of this compound, which is quite profound with this drug. Luckily, it doesn´t have adverse effects on cholesterol and, and can even lower plasma viscosity. And, since this is just testosterone, altered to be orally available (some users actually let the tablet dissolve under their tongue for increased absorbtion), we can expect many of the same results and side effects that we would with any other testosterone form (development of male sexual characteristics in women, hence they should avoid using this compound at any dose; and in men, aromatization, or conversion to estrogen is found, which can contribute to hair loss, acne, oily skin, water-retention, gynocomastia, hair growth on the body and other side effects are common). It´s also worth noting that this compound converts to DiHydroTestosterone, which can cause prostate enlargement and hair loss. Taking endogenous hormones (AAS) will affect your natural testosterone levels as well as many interrelated hormones and processes. Methyltestosterone is no exception to this rule, and taking it will result in significant decreases in plasma levels of gonadotropins, gonadal steroids, sex hormone binding globulin, free T3 and T4, and thyroid binding globulin. Inclusion of Arimidex at (.5mgs/day to help lower estrogen levels) or a similar ancillary, as well as Finasteride (Proscar) (1mg/day to help combat DHT) would be warranted with the use of Methyltestosterone. Also, when considering the possible side effects and hormonal effects Methyltestosterone can have on a user, proper Post Cycle Therapy (Nolvadex at 20mgs/day and 500iu/day of HCG for 3 weeks) is necessary.

The effect you´ll typically get from Methyltestosterone is most comparable to that of the short (or no) ester testosterones (i.e. suspension or propionate). You will get a bit stronger, but probably will not be impressed with weight gains unless intolerably high doses are used. Methyltestosterone won´t impress anyone with its ability to add weight to an athlete.

Again, in terms of cost/benefit ratio (side effects vs. results), Methyltestosterone is most effective for use prior to a weight training workout or athletic competition (or possibly to increase aggression in the weight room on a low calorie diet), and not as a weight gain or strength gain drug. Using Methyltestosterone 3-4x a week before workouts will help you derive more benefits from those workouts (and this will be especially important on a cycle), while minimizing possible issues with liver toxicity. Trying to use this compound multiple times per day and every day of the week (as would be necessary if this were the primary oral in your cycle) would not produce acceptable results (in my mind, anyway) when compared with the risks undertaken.

There are better orals than Methyltest for both size and strength, but perhaps none as good at increasing aggression. You can use this drug in conjunction with any type of cycle, as a pre-workout boost. If this drug is used as the main oral in a cycle, then the use of Methyltest should be limited to 50mgs/day for no more than 6 weeks, and after cessation, a long break from all liver-stressing compounds should be taken (i.e. oral AAS, Alcohol, etc... ).